Archive for 'Ethics' Category

Horton clears some woo

By Anthony - Last updated: Friday, January 21, 2011

Over the past three weeks the BMJ has been publishing Brian Deer‘s investigation of Wakefield’s fraudulent attempt to make money out of manufactured safety concerns about MMR. The first BMJ article dealt with the fixing of the data, the second dealt with plans to reap financial rewards from Wakefield’s deliberate stoking of fears over MMR […]

Safety in second place?

By Anthony - Last updated: Tuesday, November 30, 2010

The safety of newly marketed drugs is always provisional, based on the relatively limited population the drugs are used in prior to marketing. The number of subjects who take a drug in clinical trials is large enough to detect efficacy, but too small to detect rare, but serious, adverse events. In addition, the patients are […]

AN Wilson’s nutty Nazi comparison

By Anthony - Last updated: Thursday, November 5, 2009

Godwin’s justly celebrated law states that as an online debate grows longer, the probability of a comparison involving the Nazis or Hitler approaches one. After having explained Godwin’s Law Nick Cohen goes on to give an example of Godwin’s law in The Daily Mail, where AN Wilson attempts to equate the recently sacked Nutt with […]

Wakefield changed and misreported results

By Anthony - Last updated: Sunday, February 8, 2009

Brian Deer has been investigating Andrew Wakefield, again. THE doctor who sparked the scare over the safety of the MMR vaccine for children changed and misreported results in his research, creating the appearance of a possible link with autism, a Sunday Times investigation has found. Confidential medical documents and interviews with witnesses have established that […]

Clinical trial concerns in India

By Anthony - Last updated: Monday, January 5, 2009

Here’s a short film about ethical concerns in clinical trials in India produced by WEMOS which is worth watching:

Rimonabant withdrawal and conflicts of interest

By Anthony - Last updated: Thursday, October 23, 2008

The EMEA’s Committee for Medicinal Products for Human Use (CHMP) have pulled the marketing authorisation for rimonabant (Acomplia) [PDF]. This isn’t much of a surprise. What is interesting in this case is the reasoning, which not only addresses safety concerns, but also concerns about effectiveness in clinical practice (as opposed to clinical trials). Effectiveness, rather […]

The underbelly of science

By Anthony - Last updated: Tuesday, October 14, 2008

Kevin Leitch has an interesting post which documents Andrew Wakefield’s mistakes, although that’s probably too kind a word to use, over the years. Here is the conclusion, but you should read the whole thing. A review of the career of Andrew Wakefield is a trawl through the underbelly of science. Wakefield did not do experiments […]

Wakefield on McBride

By Anthony - Last updated: Sunday, October 12, 2008

In today’s Sunday Express a puff piece about Andrew Wakefield [not yet online] and his celeb fans has the following interesting comparison raised by Andrew Wakefield: He cites parallels between his story and that of Dr. William McBride, the Australian gynaecologist who first alerted the world to the danger of thalidomide, the morning sickness drug […]

Unrestrained badly regulated capitalism kills

By Anthony - Last updated: Thursday, September 18, 2008

Capitalism kills. There is no better example of that principle than in China. The most recent example in the news tonight is that of contaminated baby milk. China says it will launch nationwide testing of all dairy products following the deaths of three babies from contaminated milk formula. More than 6,200 babies have fallen ill […]